"AUTO-BREWERY SYNDROME"

AUTO-BREWERY SYNDROME

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A rare condition characterized by the endogenous production of ethanol in the digestive system due to fermentation of ingested carbohydrates . It requires careful diagnosis and management. Understanding its mechanisms, symptoms, and treatment options is crucial for effective care.

• Microorganisms Involved: Common organisms associated with ABS include:

  • Saccharomyces cerevisiae
  • Candida albicans
  • Klebsiella pneumoniae

Symptoms

• Intoxication Symptoms: Individuals may experience:

  • Slurred speech
  • Dizziness
  • Loss of motor coordination
  • Mood changes
  • Gastrointestinal discomfort (e.g., belching)

Diagnosis

• Testing Methods:

  • Blood tests to measure ethanol levels
  • Breathalyzers during acute episodes
  • Gas chromatography for precise measurement of ethanol in blood or breath

Treatment Options

• Immediate Care: Management of acute intoxication symptoms is essential.

• Medications:

  • Antifungals (e.g., fluconazole, micafungin) to target the overgrowth of yeast or bacteria
  • Antibiotics may be prescribed if bacterial overgrowth is identified

Case Studies

• Notable Cases:
  • A 25-year-old man with no history of alcohol consumption presented with symptoms of intoxication and was treated successfully with antifungal medication.